Psychological distress in health training: depression, anxiety and stress in health science students in Chile.
Abstract
Introduction: The mental health of health sciences students is a growing concern in medical education, given the heavy academic workload and early clinical demands that characterize their training. Objectives: To evaluate the prevalence of symptoms of depression, anxiety, and stress in health sciences students in Chile and to analyze their association with lifestyle factors relevant to the educational process. Methods: An analytical cross-sectional study was conducted with 991 students who, after providing informed consent, completed the DASS-21 (Depression, Anxiety, and Stress Scales), a 21-item self-report questionnaire designed to measure the severity of symptoms of depression, anxiety, and stress. Perceived sleep quality, physical activity, and tobacco use were also analyzed. Descriptive and bivariate analyses were performed, followed by binary logistic regression adjusted for sex and age to identify factors associated with psychological symptoms. The study was approved by a Scientific Ethics Committee. Results: A high prevalence of psychological symptoms was observed, especially anxiety (63.8%) and stress (80.3%), with greater severity in women (p < 0.001). Poor sleep quality was significantly associated with higher levels of depression, anxiety, and stress. Students with poor sleep quality were approximately three times more likely to experience depressive symptoms (AOR = 3.05; 95% CI: 2.30–4.04), stress (AOR = 3.57; 95% CI: 2.48–5.13), and anxiety (AOR = 2.78; 95% CI: 2.10–3.69). Physical activity did not show an independent association in the adjusted models, while tobacco use showed sex-specific associations. Conclusions: A high burden of emotional distress is evident among health sciences students. Sleep quality emerges as a key cross-cutting factor, reinforcing the need to incorporate institutional strategies for promoting sleep and preventing psychological distress within the educational environment.
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References
1. Martínez P, Jiménez-Molina Á, Mac-Ginty S, Martínez V, Rojas G. Salud mental en estudiantes de educación superior en Chile: una revisión de alcance con meta-análisis. Ter Psicol. 2021, 39(3), 405–426. https://doi.org/10.4067/S0718-48082021000300405
2. Agyapong-Opoku G, Agyapong B, Obuobi-Donkor G, Eboreime E. Depression and Anxiety among Undergraduate Health Science Students: A Scoping Review of the Literature. Behav Sci. 2023, 13(12), 1002. https://doi.org/10.3390/bs13121002
3. Rodríguez Flores E, Sánchez Trujillo MA. Estrés académico en estudiantes de Ciencias de la Salud en la modalidad de educación a distancia en tiempos de Covid-19. Rev Estud Exp Educ. 2022, 21(45), 51–69. https://doi.org/10.21703/0718-5162.v21.n45.2022.003
4. Garrido Bahamondes N, Macaya Suazo M, Márquez Márquez L, Orellana Yévenes I, Pereyra Hernández M, Méndez Mora Á. Percepción del estrés académico en estudiantes de Ciencias de la Salud del Maule, Chile. SANUS. 2024, 9(20), e503. https://doi.org/10.36789/sanusrevenf.vi20.503
5. Carvacho R, Morán-Kneer J, Miranda-Castillo C, Fernández-Fernández V, Mora B, Moya Y, et al. Efectos del confinamiento por COVID-19 en la salud mental de estudiantes de educación superior en Chile. Rev Med Chile. 2021, 149(3), 339–347. https://doi.org/10.4067/S0034-98872021000300339
6. Mac-Ginty S, Jiménez-Molina Á, Martínez V. Impacto de la pandemia por COVID-19 en la salud mental de estudiantes universitarios en Chile. Rev Chil Psiquiatr Neurol Infanc Adolesc. 2021, 32(1), 23–37.
7. Martínez-Líbano J. Prevalence and variables associated with depression, anxiety, and stress among Chilean higher education students post-pandemic. Front Psychiatry. 2023, 14, 1–10. https://doi.org/10.3389/fpsyt.2023.1139946
8. Malebari AM, Alamoudi SO, Al-Alawi TI, Alkhateeb AA, Albuqayli AS, Alothmany HN. Prevalence of depression and anxiety among university students in Jeddah, Saudi Arabia: exploring sociodemographic and associated factors. Front Public Health. 2024, 12: 1441695. https://doi.org/10.3389/fpubh.2024.1441695
9. Gao W, Ping S, Liu X. Gender differences in depression, anxiety, and stress among college students: A longitudinal study from China. J Affect Disord. 2020, 263, 292–300. https://doi.org/10.1016/j.jad.2019.11.121
10. Lillo I, Crockett MA, Errázuriz A, Martínez V. Co-ocurrencia de problemas de salud mental en estudiantes universitarios y su relación con variables sociodemográficas. Rev Med Chile. 2025, 153(7), 505–516. https://doi.org/10.4067/S0034-98872025000700505
11. Valdés JM, Díaz FJ, Christiansen PM, Lorca GA, Solorza FJ, Alvear M, et al. Mental health and related factors among undergraduate students during SARS-CoV-2 pandemic: a cross-sectional study. Front Psychiatry. 2022, 13, 833263. https://doi.org/10.3389/fpsyt.2022.833263
12. Aveiro-Róbalo TR, Garlisi-Torales LD, Nati-Castillo HA, Valeriano-Paucar JR, García-Arévalo CM, Ayala-Servín N, et al. Ansiedad y depresión en estudiantes de medicina de Latinoamérica durante la pandemia del COVID-19. RSPP. 2023, 13(1), 40–45. https://doi.org/10.29393/ce28-19sdjr30019
13. Zapata Ramírez A, Morlett Chávez JA, Cepeda Nieto AC, Esquivel Muñoz G, Aleida Flores C, González Tovar J, et al. Depresión, ansiedad, estrés y bienestar psicológico en estudiantes de medicina. Ciencia Cierta. 2025, 21(82), 149–170. https://revistas.uadec.mx/CienciaCierta/article/view/234
14. Lovibond PF, Lovibond SH. The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. Behav Res Ther. 1995, 33(3), 335–343. https://doi.org/10.1016/0005-7967(94)00075-U
15. Antúnez Z, Vinet EV. Escalas de depresión, ansiedad y estrés (DASS-21): Validación de la versión abreviada en estudiantes universitarios chilenos. Rev Med Chile. 2012, 140(9), 1123–1129. https://doi.org/10.4067/S0034-98872012000900005
16. Kumar B, Shah MAA, Kumari R, Kumar A, Kumar J, Tahir A. Depression, Anxiety, and Stress Among Final-year Medical Students. Cureus. 2019, 11(3), e4257. https://doi.org/10.7759/cureus.4257
17. Zeng W, Chen R, Wang X, Zhang Q, Deng W. Prevalence of mental health problems among medical students in China: A meta-analysis. Medicine. 2019, 98(18), e15337. https://doi.org/10.1097/MD.0000000000015337
18. García-Marchant C, García-Marchant P, Guajardo-Valencia M, Rojas-Henríquez E, Mora-Tapia F, Araya-Galleguillos F. Asociación entre depresión y ansiedad con el bienestar subjetivo en estudiantes de medicina de Atacama. Rev Chil Neuro-Psiquiat. 2024, 62(4), 326–336. https://doi.org/10.4067/S0717-92272024000400326
19. Leyton-Hernández Á, Cuello Cortés B, Fredes Castro S, Gutiérrez Concha A, Carvajal Jofré M, Molina Cortés M. Relación entre prácticas clínicas y salud mental en estudiantes de enfermería. Rev Chil Enferm. 2025, 7, 78082. https://doi.org/10.5354/2452-5839.2025.78082
20. Zhang Y, He J, Ruan H, Yao P, Ma G. The impact of physical exercise on mental health. Front Psychol. 2025, 16, 1609415. https://doi.org/10.3389/fpsyg.2025.1609415
21. Li B, Jiang W, Han SS, Ye YP, Li YX, Lou H, et al. Influence of physical activity on depression levels. BMC Public Health. 2024, 24, 1023. https://doi.org/10.1186/s12889-024-18433-w
22. Zhu Y, Liang WM, Jiang K, Truskauskaitė I, Griškova-Bulanova I, Bai Z, et al. Mental well-being of college students. BMC Public Health. 2025, 25(1), 3038. https://doi.org/10.1186/s12889-025-24231-9
23. Sheikh A, Payne-Cook C, Lisk S, Carter B, Brown JSL. Why do young men not seek help? Eur Child Adolesc Psychiatry. 2025, 34, 565–583. https://doi.org/10.1007/s00787-024-02520-9
24. Buecker S, Simacek T, Ingwersen B, Terwiel S, Simonsmeier BA. Physical activity and subjective well-being. Health Psychol Rev. 2021, 15(4), 574–592. https://doi.org/10.1080/17437199.2020.1760728
25. Rodríguez-Romo G, Acebes-Sánchez J, García-Merino S, Garrido-Muñoz M, Blanco-García C, Diez-Vega I. Physical Activity and Mental Health. Int J Environ Res Public Health. 2022, 20(1), 195. https://doi.org/10.3390/ijerph20010195
26. Santana EES, Neves LM, Souza KC, Mendes TB, Rossi FE, Silva AAD, et al. Physically inactive students and mental health. Int J Environ Res Public Health. 2023, 20(5), 4494. https://doi.org/10.3390/ijerph20054494
27. Ballester-Martínez O, Baños R, Navarro-Mateu F. Actividad física y bienestar mental. Cuad Psicol Deporte. 2022, 22(2), 62–84.
28. Prada Rozo MJ, Cuevas Gómez RD. Sedentarismo y barreras en estudiantes. Revie. 2022, 9(2), 69–85. https://doi.org/10.47554/revie.vol9.num2.2022.pp69-85
29. Vera V, Oñate G, Fernández M, Valladares M, Crovetto M, Espinoza M, et al. Mena F. Tobacco consumption in Chilean university students. J Prev Med Hyg. 2021, 62(2), E430–E438. https://doi.org/10.15167/2421-4248/jpmh2021.62.2.1868
30. López-Cisneros MA, Telumbre-Terrero JY, Graniel-Thompson LG, Díaz-Villanueva GA, Contreras-Rodríguez LC. Consumo de tabaco y alcohol en jóvenes universitarios. CMS-BUAP. 2024, 5(10), 21–34.
31. Ministerio de Salud (Chile). Encuesta Nacional de Salud 2016–2017: segundo informe de resultados. Santiago: Ministerio de Salud, 2018. https://redsalud.ssmso.cl/wp-content/uploads/2018/02/2-Resultados-ENS_MINSAL_31_01_2018-ilovepdf-compressed.pdf
32. López-Alonso A, Liébana-Presa C, Sánchez-Valdeón L, López-Aguado M, Quiñones-Pérez M, Fernández-Martínez E. La universidad como entorno saludable. Enferm Glob. 2021, 20(63), 221–243. https://doi.org/10.6018/eglobal.441601
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