Comorbilidad de TEA y TDAH: revisión sistemática de los avances en investigación
Resumen
La reciente publicación del DSM-5, introduce la novedad de aceptar la posibilidad de un diagnóstico comórbido del Trastorno por Déficit de Atención/Hiperactividad (TDAH) y el Trastorno de Espectro Autista (TEA).
En este artículo se realiza una revisión de trabajos que han estudiado esta comorbilidad. Se revisaron un total de 40 investigaciones, estableciendo 7 temáticas diferentes. Se observó que la presencia del TDAH en el TEA aumentaba la severidad de la sintomatología autista y que su comorbilidad estaba relacionada con tasas más altas de comportamientos disruptivos, de estrés parental, y una calidad de vida y habilidades sociales más pobresDescargas
Citas
American Psychiatric Association. (1994). Diagnostic and Statistical Manual of Mental Disorders (4ª ed.)(DSM-IV). Washington DC (EEUU): APA.
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders (5ª ed.)(DSM-V). Washington DC (EEUU): APA
Baio, J. (2012). Prevalence of Autism Spectrum Disorders: autism and developmental disabilities monitoring network, 14 Sites, United States, 2008. Morbidity and mortality weekly report. Surveillance Summaries. Centers for Disease Control and Prevention, 61(3), 1-19.
*Barnard-Brak, L., Sulak, T. N., y Fearon, D. D. (2011). Coexisting disorders and academic achievement among children with ADHD. Journal of Attention Disorders, 15(6), 506-515. doi: 10.1177/1087054710369667
Baron-Cohen, S., Scott, F. J., Allison, C., Williams, J., Bolton, P., Matthews, F. E., y Brayne, C. (2009). Prevalence of autism-spectrum conditions: UK school-based population study. The British Journal of Psychiatry, 194(6), 500-509. doi: 10.1192/bjp.bp.108.059345
Cardo, E., Servera, M., Vidal, C., De Azua, B., Redondo, M., y Riutort, L. (2011). Influencia de los diferentes criterios diagnósticos y la cultura en la prevalencia del trastorno por déficit de atención/hiperactividad. Revista de Neurología, 52(Supl 1), 109-17.
De la Iglesia Gutiérrez, M., y Olivar Parra, J. S. (2012). Revisión de estudios e investigaciones relacionadas con la comorbilidad diagnóstica de los Trastornos del Espectro del Autismo de Alto Funcionamiento (TEA-AF) y los trastornos de ansiedad. Anales de Psicología, 28(3), 823-833. doi: 10.6018/analesps.28.3.124881
De Zwaan, M., Gruß, B., Müller, A., Graap, H., Martin, A., Glaesmer, H., ... y Philipsen, A. (2012). The estimated prevalence and correlates of adult ADHD in a German community sample. European Archives of Psychiatry and Clinical Neuroscience, 262(1), 79-86. doi: 10.1007/s00406-011-0211-9
Ekas, N., y Whitman, T. L. (2010). Autism symptom topography and maternal socioemotional functioning. Journal Information, 115(3), 234-249. doi: http://dx.doi.org/10.1352/1944-7558-115.3.234
Fombonne, E. (2003). Epidemiological surveys of autism and other pervasive developmental disorders: an update. Journal of Autism and Developmental Disorders, 33(4), 365-382. doi: 10.1023/A:1025054610557
Fombonne, E. (2005). The changing epidemiology of autism. Journal of Applied Research in Intellectual Disabilities, 18(4), 281-294. doi: 10.1111/j.1468-3148.2005.00266.x
Frazier, T. W., Youngstrom, E. A., Speer, L., Embacher, R., Law, P., Constantino, J., … y Eng., C. (2012). Validation of proposed DSM-5 criteria for autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 51(1), 28–40. doi: 10.1016/j.jaac.2011.09.021
*Gadow, K. D., DeVincent, C. J., y Pomeroy, J. (2006). ADHD symptom subtypes in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36(2), 271-283. doi: 10.1007/s10803-005-0060-3
Gargaro, B. A., Rinehart, N. J., Bradshaw, J. L., Tonge, B. J., y Sheppard, D. M. (2011). Autism and ADHD: how far have we come in the comorbidity debate? Neuroscience & Biobehavioral Reviews, 35(5), 1081-1088. doi: 10.1016/j.neubiorev.2010.11.002
Getahun, D., Jacobsen, S. J., Fassett, M. J., Chen, W., Demissie, K., y Rhoads, G. G. (2013). Recent trends in childhood attention-deficit/hyperactivity disorder. JAMA pediatrics, 167(3), 282-288.doi: 10.1001/2013.jamapediatrics.401.
*Gjevik, E., Eldevik, S., Fjæran-Granum, T., y Sponheim, E. (2011). Kiddie-SADS reveals high rates of DSM-IV disorders in children and adolescents with autism spectrum disorders. Journal of Autism and Developmental Disorders, 41(6), 761-769. doi: 10.1007/s10803-010-1095-7
*Goldin, R. L., Matson, J. L., Tureck, K., Cervantes, P. E., y Jang, J. (2013). A comparison of tantrum behavior profiles in children with ASD, ADHD and comorbid ASD and ADHD. Research in Developmental Disabilities, 34(9), 2669-2675. doi: 10.1016/j.ridd.2013.04.022
*Goldstein, S., y Schwebach, A. J. (2004). The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: results of a retrospective chart review. Journal of Autism and Developmental Disorders, 34(3), 329-339. doi: 10.1023/B:JADD.0000029554.46570.68
*Grzadzinski, R., Di Martino, A., Brady, E., Mairena, M. A., O’Neale, M., Petkova, E., ... y Castellanos, F. X. (2011). Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD? Journal of Autism and Developmental Disorders, 41(9), 1178-1191. doi: 10.1007/s10803-010-1135-3
*Hanson, E., Cerban, B. M., Slater, C. M., Caccamo, L. M., Bacic, J., y Chan, E. (2013). Brief report: Prevalence of attention deficit/hyperactivity disorder among individuals with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 43(6), 1459-1464. doi: 10.1007/s10803-012-1677-7
Hayes, S. A., y Watson, S. L. (2013). The impact of parenting stress: A meta-analysis of studies comparing the experience of parenting stress in parents of children with and without autism spectrum disorder. Journal of Autism and Developmental Disorders, 43(3), 629-642. doi: 10.1007/s10803-012-1604-y
*Holtmann, M., Bölte, S., y Poustka, F. (2007). Attention deficit hyperactivity disorder symptoms in pervasive developmental disorders: association with autistic behavior domains and coexisting psychopathology. Psychopathology, 40(3), 172-177. doi: 10.1159/000100007
Hsu, S. W., Chiang, P. H., Lin, L. P., y Lin, J. D. (2012). Disparity in autism spectrum disorder prevalence among Taiwan National Health Insurance enrollees: Age, gender and urbanization effects. Research in Autism Spectrum Disorders, 6(2), 836-841. doi: 10.1016/j.rasd.2011.09.006
Huerta, M., Bishop, S. L., Duncan, A., Hus, V., y Lord, C. (2012). Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders. American Journal of Psychiatry, 169(10), 1056-1064. doi: 10.1176/appi.ajp.2012.12020276
*Jang, J., Matson, J. L., Cervantes, P. E., y Goldin, R. L. (2013b). The relationship between race and comorbid symptoms in infants and toddlers with autism spectrum disorder. Research in Autism Spectrum Disorders, 7(11), 1433-1438. doi: 10.1016/j.rasd.2013.08.011
*Jang, J., Matson, J. L., Williams, L. W., Tureck, K., Goldin, R. L., y Cervantes, P. E. (2013a). Rates of comorbid symptoms in children with ASD, ADHD, and comorbid ASD and ADHD. Research in Developmental Disabilities, 34(8), 2369-2378. doi: 10.1016/j.ridd.2013.04.021
Kaland, N. (2011). Brief report: should Asperger syndrome be excluded from the forthcoming DSM-V? Research in Autism Spectrum Disorders, 5(3), 984-989. doi: 10.1016/j.rasd.2011.01.011
*Konst, M. J., Matson, J. L., y Turygin, N. (2013). Comparing the rates of tantrum behavior in children with ASD and ADHD as well as children with comorbid ASD and ADHD diagnoses. Research in Autism Spectrum Disorders, 7(11), 1339-1345. doi: 10.1016/j.rasd.2013.07.023
*Kotte, A., Joshi, G., Fried, R., Uchida, M., Spencer, A., Woodworth, K. Y., ... & Biederman, J. (2013). Autistic traits in children with and without ADHD. Pediatrics, 132(3), e612-e622. doi: 10.1542/peds.2012-3947
*Lee, D. O., y Ousley, O. Y. (2006). Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders. Journal of Child & Adolescent Psychopharmacology, 16(6), 737-746. doi: 10.1089/cap.2006.16.737
Lin, J. D., Sung, C. L., Lin, L. P., Hsu, S. W., Chien, W. C., Su, S. L., y Wu, J. L. (2011). Ten-year trend analysis of autism severity: A nationwide population-based register study. Research in Autism Spectrum Disorders, 5(1), 570-574. doi: 10.1016/j.rasd.2010.06.024
Lyons, A. M., Leon, S. C., Phelps, C. E. R., y Dunleavy, A. M. (2010). The impact of child symptom severity on stress among parents of children with ASD: The moderating role of coping styles. Journal of Child and Family Studies, 19(4), 516-524. doi: 10.1007/s10826-009-9323-5
*Mannion, A., Leader, G., y Healy, O. (2013). An investigation of comorbid psychological disorders, sleep problems, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder. Research in Autism Spectrum Disorders, 7(1), 35-42. doi: 10.1016/j.rasd.2012.05.002
Martín-Fernández, J. D. (2013). La (no) decepción del DSM-5. Cuadernos de Neuropsicología, 7(1), 9-21.
Matson, J. L., y Kozlowski, A. M. (2011). The increasing prevalence of autism spectrum disorders. Research in Autism Spectrum Disorders, 5(1), 418-425. doi: 10.1016/j.rasd.2010.06.004
*May, T., Rinehart, N., Wilding, J., y Cornish, K. (2013). The role of attention in the academic attainment of children with autism spectrum disorder. Journal ofAutism and Developmental Disorders, 43(9), 2147-2158. doi: 10.1007/s10803-013-1766-2
Mazurek, M. O., Vasa, R. A., Kalb, L. G., Kanne, S. M., Rosenberg, D., Keefer, A., ... y Lowery, L. A. (2013). Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. Journal of Abnormal Child Psychology, 41(1), 165-176. doi: 10.1007/s10802-012-9668-x
*Miranda, A., Tárraga, R., Fernández, M. I., Colomer, C., y Pastor, G. (2015). Parenting Stress in Families of Children with Autism Spectrum Disorder and ADHD. Exceptional Children, preprint.doi: 10.1177/00144029155854790014402915585479.
Polanczyk, G., de Lima, M. S., Horta, B. L., Biederman, J., y Rohde, L. A. (2007). The worldwide prevalence of ADHD: a systematic review and metaregression analysis. The American journal of psychiatry, 164(6), 942-948. doi: 10.1176/ajp.2007.164.6.942
Pozo, P., y Sarriá, E. (2014). Un modelo global de estrés en padres de personas con trastornos del espectro autista. Anales de Psicología, 30(1), 180-191. doi: 10.618/analesps.30.1.140722
*Rao, P. A., y Landa, R. J. (2014). Association between severity of behavioral phenotype and comorbid attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders. Autism, 18(3), 272-280. doi: 10.1177/1362361312470494
*Reiersen, A. M., Constantino, J. N., Volk, H. E., y Todd, R. D. (2007). Autistic traits in a population‐based ADHD twin sample. Journal of Child Psychology and Psychiatry, 48(5), 464-472. doi: 10.1111/j.1469-7610.2006.01720.x
Ritvo, E. R. (2012). Postponing the proposed changes in DSM 5 for autistic spectrum disorder until new scientific evidence adequately supports them. Journal of Autism and Developmental Disorders, 42(9), 1-2. doi: 10.1007/s10803-012-1613-x
*Russell, G., Rodgers, L. R., Ukoumunne, O. C., y Ford, T. (2014). Prevalence of parent-reported ASD and ADHD in the UK: findings from the Millennium Cohort Study. Journal of Autism and Developmental Disorders, 44(1), 31-40. doi: 10.1007/s10803-013-1849-0
*Sikora, D. M., Vora, P., Coury, D. L., y Rosenberg, D. (2012). Attention-deficit/hyperactivity disorder symptoms, adaptive functioning, and quality of life in children with autism spectrum disorder. Pediatrics, 130(2), 91-97. doi: 10.1542/peds.2012-0900G
Simon, V., Czobor, P., y Bitter, I. (2013). Is ADHD severity in adults associated with the lifetime prevalence of comorbid depressive episodes and anxiety disorders? European Psychiatry, 28(5), 308-314. doi: 10.1016/j.eurpsy.2012.05.002
*Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., y Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921-929. doi: 10.1097/CHI.0b013e318179964f
*Sinzig, J., Walter, D., y Doepfner, M. (2009). Attention Deficit/Hyperactivity Disorder in children and adolescents with Autism Spectrum Disorder symptom or syndrome? Journal of Attention Disorders, 13(2), 117-126. doi: 10.1177/1087054708326261
Sivertsen, B., Posserud, M. B., Gillberg, C., Lundervold, A. J., y Hysing, M. (2012). Sleep problems in children with autism spectrum problems: a longitudinal population-based study. Autism, 16(2), 139-150. doi: 10.1177/1362361311404255
*Sprenger, L., Bühler, E., Poustka, L., Bach, C., Heinzel-Gutenbrunner, M., Kamp-Becker, I., y Bachmann, C. (2013). Impact of ADHD symptoms on autism spectrum disorder symptom severity. Research in Developmental Disabilities, 34(10), 3545-3552. doi: 10.1016/j.ridd.2013.07.028
Theule, J., Wiener, J., Tannock, R., y Jenkins, J. M. (2013). Parenting stress in families of children with ADHD. A Meta-Analysis. Journal of Emotional and Behavioral Disorders, 21(1), 3-17. doi: 10.1177/1063426610387433
*Tureck, K., Matson, J. L., May, A., y Turygin, N. (2013). Externalizing and tantrum behaviours in children with ASD and ADHD compared to children with ADHD. Developmental Neurorehabilitation, 16(1), 52-57. doi: 10.3109/17518423.2012.719245
*Turygin, N., Matson, J. L., y Tureck, K. (2013). ADHD symptom prevalence and risk factors in a sample of toddlers with ASD or who are at risk for developmental delay. Research in developmental disabilities, 34(11), 4203-4209. doi:10.1016/j.ridd.2013.07.020
*Van Steijn, D. J., Oerlemans, A. M., van Aken, M. A., Buitelaar, J. K., y Rommelse, N. N. (2013). Match or mismatch? Influence of parental and offspring ASD and ADHD symptoms on the parent–child relationship. Journal of Autism and Developmental Disorders, 43(8), 1935-1945. doi: 10.1007/s10803-012-1746-y
*Van Steijn, D. J., Oerlemans, A. M., van Aken, M. A., Buitelaar, J. K., y Rommelse, N. N. (2014). The reciprocal relationship of ASD, ADHD, depressive symptoms and stress in parents of children with ASD and/or ADHD. Journal of Autism and Developmental Disorders, 44(5), 1-13. doi: 10.1007/s10803-013-1958-9
Wing, L., Gould, J., y Gillberg, C. (2011). Autism spectrum disorders in the DSM-V: better or worse than the DSM-IV? Research in Developmental Disabilities, 32(2), 768-773. doi: 10.1016/j.ridd.2010.11.003
*Yerys, B. E., Wallace, G. L., Sokoloff, J. L., Shook, D. A., James, J. D., y Kenworthy, L. (2009). Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders. Autism Research, 2(6), 322-333. doi: 10.1002/aur.103
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