Evaluating Students’ Performance and Perceptions Following Simulated Pharmacology Laboratories.
Abstract
Background: Traditional pharmacology education fails to bridge the gap between theoretical drug mechanisms and clinical application. This study evaluates the implementation of a simulated pharmacology laboratory as a pedagogical tool to enhance student achievement. Methods: A mixed-methods study was conducted across three student cohorts (n = 308). The simulation was integrated into: Principles of Disease I & II, Gastrointestinal (GI) System, and Nervous System & Special Senses modules. Performance was measured via pharmacology OSPE stations. Data were analyzed using SPSS, employing ANOVA and t-tests for gender-stratified quantitative results. Qualitative reliability was ensured through a thematic analysis of feedback from students, medical educators, and pharmacology experts. Results: Quantitative analysis revealed high levels of performance outcomes, particularly in the GI module (Mean 8.7 ± 0.1 for Patch 3 females). However, the Nervous System module consistently yielded lowest scores (Means < 7.0) across all patches, suggesting inherent conceptual complexity. Statistical significance was observed in Principles of Disease I (p < 0.05). Qualitatively, experts (n=10) praised the method's resource efficiency and cognitive alignment but cautioned against lack of biological variability inherent in digital models. Students reported increased self-efficacy, though gender-stratified feedback highlighted differing preferences for collaborative versus technical preparatory materials. Conclusion: Simulated pharmacology labs significantly support undergraduate learning outcomes in specific modular domains. While highly effective for visualizing drug-receptor interactions, a "hybrid" model incorporating real-world biological variability is recommended for complex neuropharmacology topics. These findings support the wider integration of simulation-based learning (SBL) as a stable, equitable pedagogical framework in medical curricula.
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References
1. Zorrilla E, Mazzitelli CA, & Tomasina F. Laboratory practices in medical education: teaching perceptions and pedagogical challenges. Spanish Journal of Medical Education 2026, 7(5). https://doi.org/10.6018/edumed.720881
2. Shanmugapriya S, Umamaheshwari A, Bhuvaneswari K. Exploring Faculty Perspectives on Implementing Simulation-Based Learning in Pharmacology: A Qualitative Focus Group Study. Annals of Medicine and Medical Sciences 2026, 187-191. https://ammspub.com/index.php/amms/article/view/470
3. Elamin A, Ali MF, & Almarabheh A. Impact of simulation-based learning on the academic performance of medical students during pediatric clerkships. BMC Med Educ. 2025, 25(1), 1300. http://doi.org/10.1186/s12909-025-07911-3
4. Alshammari A, Innab A, Nahari A, Alanazi H, Alanazi R, & Almukhaini G. Impact of Simulation-Based Learning on Learning Loss Among Nursing Students: A Quasi-Experimental Study. The International Review of Research in Open and Distributed Learning 2025, 26(1), 80–98. https://doi.org/10.19173/irrodl.v26i1.7984
5. Laverde AC, Álvarez RA, Álvarez TA, & Parra SLN. Simulation-Based Learning Impact on Medical Students. Interdisciplinary Formative Approach. Journal of Posthumanism 2025, 5(6), 4060-4071. https://doi.org/10.63332/joph.v5i6.2578
6. Moll-Khosrawi P, Zöllner C, Cronje JS, & Schulte-Uentrop L. The effects of simulation-based education on medical students' motivation. Int J Med Educ. 2021, 12, 130-135. http://doi.org/10.5116/ijme.60c0.981e
7. Santos A, Gabrielli Â, Lima A, Bruch G, & Almeida A. Simulation in medical graduation: teaching of pharmacology. Revista Brasileira de Educação Médica. 2025, 49 (2), e077. http://doi.org/10.1590/1981-5271v49.2-2023-0171.ing
8. Chung CH. Enhancing medical student learning through virtual pharmacology simulations: a pre-post evaluation study. BMC Med Educ. 2026, 26(1), 253. https://doi.org/10.1186/s12909-026-08624-x
9. Lledó L, Pérez-García F, Rojas AC, Pérez-Tanoira R, & Cuadros-González J. Curricular insertion of clinical simulation in Medical Microbiology: design and implementation. Spanish Journal of Medical Education. 2026, 7(5). https://doi.org/10.6018/edumed.722901
10. Safaeipour R, Aalaa M, Mojtahedzadeh R, Mohammadi A, Asadzandi S, & Mousavi A. Virtual or blended laboratories for healthcare students education: a systematized review. BMC Med Educ. 2025, 25(1): 1352. https://doi.org/10.1186/s12909-025-07937-7
11. Malhotra K, Balakrishnan H, Warmington E, Soran V, Crowe F, Zhou D, Kempegowda P, et al. Global Disparities in Simulation-Based Learning Performance: Serial Cross-Sectional Mixed Methods Study. JMIR Med Edu. 2025, 11, e52332. https://doi.org/10.2196/52332
12. Al-Sofyani KA. Gender-based perception of undergraduate medical students at King Abdulaziz University toward use of simulation-based learning in pediatrics. J Contemp Med Edu. 2018, 7(2), 21–27. http://doi.org/10.5455/jcme.20180526101034
13. Abdel Haleem SA, Ahmed AA, El Bingawi H, et al. Medical Students' Perception of Virtual Simulation-Based Learning in Pharmacology. Cureus 2023, 15(1), e33261. http://doi.org/10.7759/cureus.33261
14. Diaz Medina BA, Ruiz Gomez LM, Bernal Bravo M, Padilla Guerrero JM, Razo Jimenez G, Torres Rodriguez LE, & Villanueva Duque JA. Perceptions and attitudes of undergraduate medical students regarding the use of the simulation-based learning model: a mixed study. Spanish Journal of Medical Education 2025, 6(1). https://doi.org/10.6018/edumed.638511
15. Kj DP, K R, Dgsr KM, Reddy YN, et al.. Impact of Simulation Based Learning on Knowledge and Skills Among Medical Students Undergoing Competency Based Medical Education. Cureus 2025, 17(7): e88749. https://doi.org/10.7759/cureus.88749
16. Elendu C, Amaechi DC, Okatta AU, Amaechi EC, Elendu TC, Ezeh CP, & Elendu ID. The impact of simulation-based training in medical education: A review. Medicine (Baltimore). 2024, 103(27), e38813. https://doi.org/10.1097/MD.0000000000038813
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