CEREBROSPINAL FLUID PRESSURES IN RAT AFTER PERMANENT IMPLATATION OF A CATHETER IN THE LATERAL VENTRICIE
Abstract
Ten male Wistar rats weighing 450 g were used to study the possibilily of replacing artiticial cerebrospinal fluid by sterile physiological serum (SPS), in determinating the cerebrospinal fluid pressure in the lateral ventricles. The time needed to obtain a level registration with our method was also studied. Twenty-four hours after the implantation of the catheter in the left lateral ventricle (performed between 9 a.m. and 17 p.m.) 0.1 ml SPS was inyected, recording pressure and the time necessary for its stabilization. Each animal was tested three times, on successive days. The observed mean pressure was 130 ± 22 mm H,O. Mean stabilization time was 15.67 ± 8 minutes. These results are comparable to the data reported by several authors using artificial cerebrospinal fluid, supporting the usefulness and exactitude of our method.Downloads
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