Variables associated with adverse events in neonates with peripherally inserted central catheters
Abstract
Objective: To identify the factors associated with the occurrence of adverse events by a peripherally inserted central catheter in newborns.
Methods: A quantitative, cross-sectional study carried out in the Neonatal Intensive Care Unit of a reference maternity hospital in high-risk maternal and child care in Northeast Brazil. The sample of 108 neonates was collected from February to November 2016.
Results: The prevalence of adverse events in newborns was 53.70%, associated with the following variables: male gender (p=0.033), weight below 2500 grams (p=0.003), insertion performed after 48 hours of life (p=0.027), more than three puncture attempts (p=0.024), difficulty in inserting the catheter (p=0.040), intercurrence during catheter insertion (p=0.027), over two dressing changes (p=0.009), and non-central position of the device (p=0.042).
Conclusion: The results indicate the need for strategies to prevent adverse events, with emphasis on continuing education and on the improvement of skills regarding the use of this device.
Downloads
References
Sharpe E, Kuhn L, Ratz D, Krein SL, Chopra V. Neonatal Peripherally Inserted Central Catheter Practices and Providers: Results From the Neonatal PICC 1 Survey. Adv Neonatal Care [Internet]. 2017 [acesso em: 05 jun. 2018];17(3):209-221. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/28045704.
Ling Q, Chen H, Tang M, Qu Y, Tang B. Accuracy and Safety Study of Intracavitary Electrocardiographic Guidance for Peripherally Inserted Central Catheter Placement in Neonates. J Perinat Neonatal Nurs [Internet]. 2019 [acesso em: 05 jun. 2018];33(1):89-95. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/30676468.
Di Santo MK, Takemoto D, et al. Peripherally inserted central venous catheters: alternative or first choice vascular access?. J Vasc Bras [Internet]. 2017 [acesso em: 10 jun. 2018];16(2):104-112. Disponível em: http://dx.doi.org/10.1590/1677-5449.011516.
Chopra V, Flanders AS, Saint S, Woller SC, O'Grady NP, Safdar N, et al. The Michigan appropriateness guide for intravenous catheters (MAGIC): results from a multispecialty panel using the RAND/UCLA appropriateness method. Ann Intern Med [Internet]. 2015 [acesso em: 15 jun. 2018];15;163(6 Suppl):S1-40. Disponível em: https://doi.org/10.7326/M15-0744.
Chen IL, Ou-Yang MC, Chen FS, Chung MY, Chen CC, Liu YC, et al. The equations of the inserted length of percutaneous central venous catheters on neonates in NICU. PediatrNeonatol [Internet]. 2018 [acesso em 20 jul. 2018]; pii: S1875-9572(18)30283-3. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/30217481.
Rosche N, Stehr W. Evaluation of a Magnetic Tracking and Electrocardiogram-based Tip Confirmation System for Peripherally Inserted Central Catheters in Pediatric Patients. J Infus Nurs [Internet]. 2018 [acesso em 02 ago. 2018]; 41(5):301-8. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/30188452.
Chenoweth KB, Guo JW, Chan B. The Extended Dwell Peripheral Intravenous Catheter Is an Alternative Method of NICU Intravenous Access. Adv Neonatal Care [Internet]. 2018 [acesso em 10 ago. 2018];18(4):295-30. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/29847401.
Dongara AR, Patel DV, Nimbalkar SM, Potana N, Nimbalkar AS. Umbilical Venous Catheter Versus Peripherally Inserted Central Catheter in Neonates: A Randomized Controlled Trial. J Trop Pediatr [Internet]. 2017 [acesso em 20 ago. 2018]; 1;63(5):374-9. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/28077611.
Vachharajani AJ, Vachharajani NA, Morris H, Niesen A, Elward A, Linck DA, et al. Reducing peripherally inserted central catheters in the neonatal intensive care unit. J Perinatol [Internet]. 2017 [acesso em 05 set. 2018];37(4):409-413. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/28079867.
Ling QY, Chen H, Tang M, Qu Y, Tang BZ. Efficiency of electrocardiogram monitor for positioning the catheter tip in peripherally inserted central catheter placement in neonates. Zhongguo Dang Dai ErKeZaZhi [Internet]. 2018 [acesso em 16 set. 2018];20(5):363-7. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/29764571.
Vieira S. Introdução à Bioestatística. 5th ed. Rio de Janeiro: Elsevier; 2015.
Costa P, Silva MN, Kimura AF. Intravenous therapy and non-elective removal of epicutaneous catheters: a cohort study of neonates. Online Braz J Nurs [Internet]. 2014 [acesso em 05 out. 2018]; 13(2):129-38. Disponível em: http://www.objnursing.uff.br/index.php/nursing/article/view/4572.
Dubbink-Verheij GH, Bekker V, Pelsma ICM, van Zwet EW, Smits-Wintjens VEHJ, Steggerda SJ, te Pas AB and Lopriore E. Blood stream Infection Incidence of Different Central Venous Catheters in Neonates: A Descriptive Cohort Study. Front. Pediatr [Internet]. 2017 [acesso em 18 out. 2018];5:142. Disponível em: http://dx.doi.org/10.3389%2Ffped.2017.00142.
Duarte ED, Pimenta AM, Silva BCN, Paula CM. Fatores associados à infecção pelo uso do cateter central de inserção periférica em Unidade de Terapia Intensiva Neonatal. Rev Esc Enferm USP [Internet]. 2013 [acesso em 15 nov. 2018]; 47(3):547-54. Disponível em: http://www.scielo.br/pdf/reeusp/v47n3/0080-6234-reeusp-47-3-00547.pdf.
Uygun I. Peripherally inserted central catheter in neonates: A safe and easy insertion technique. J Pediatr Surg [Internet]. 2016 [acesso em 02 dez 2018];51(1):188-91. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/26364881.
Johnson KN, Thomas T, Grove J, Jarboe MD. Insertion of peripherally inserted central catheters in neonates less than 1.5 kg using ultrasound guidance. Pediatr Surg Int [Internet]. 2016 [acesso em 17 dez 2018];32(11):1053-1057. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/27590475.
Yu X, Yue S, Wang M, Cao C, Liao Z, Ding Y, et al. Risk Factors Related to Peripherally Inserted Central Venous Catheter Nonselective Removal in Neonates. Biomed Res Int [Internet]. 2018 [acesso em 12 fev 2019]; 30;2018:3769376. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/30003096.
Silva R, Lui A, Ferreira H, Franca A, Lala E, Vieira C. Analys in the use of peripherally inserted central cateter in neonatology. Journal of Nursing UFPE on line [Internet]. 2016 [acesso em 24 fev 2019];10(2):796-804. Disponível em: https://periodicos.ufpe.br/revistas/revistaenfermagem/article/view/11022.
Costa P, Kimura AF, Brandon DH, Damiani LP. Predictors of non elective removal of peripherally inserted central catheters in infants. Biol Res Nurs [Internet]. 2016 [acesso em 04 fev 2019]; 18(2):173-80. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/26134427.
Litz CN, Tropf JG, Danielson PD, Chandler NM. The idle central venous catheter in the NICU: When should it be removed? J PediatrSurg [Internet]. 2018 [acesso em 16 fev 2019];Jul;53(7):1414-1416. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/29198897.
Stroud A, Zalieckas J, Tan C, Tracy S, Zurakowski D, Mooney DP. Simple formulas to determine optimal subclavian central venous catheter tip placement in infants and children. J Pediatr Surgery [Internet]. 2014 [acesso em 10 mai 2019];49:1109–112. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/24952798.
Dasgupta N, Patel MN, Racadio JM, Johnson ND, Lungren MP. Comparison of complications between pediatric peripherally inserted central catheter placement techniques. Pediatr Radiol [Internet]. 2016 [acesso em 14 mai 2019];46(10):1439-43. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/27126700.
Lui AML, Zilly A, França AFO, Ferreira H, Toninato APC, da Silva RMM. Care and limitations in the management of the peripherally inserted central catheter in neonatology. Revista de Enfermagem do Centro-Oeste Mineiro [Internet]. 2018 [acesso em 16 mai 2019 ]; 8:e1918. Disponível em: http://www.seer.ufsj.edu.br/index.php/recom/article/view/1918/1901.
Gupta R, Drendel AL, Hoffmann RG, Quijano CV, Uhing MR. Migration of Central Venous Catheters in Neonates: A Radiographic Assessment. Am J Perinatol [Internet]. 2016 [acesso em 20 mai 2019];33(6):600-4. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/26731179.
Souza RRB, Alves VH, Rodrigues DP, Dames LJP, Medeiros FVA, Paiva ED. The knowledge of nurses in terms of the peripherally inserted central catheter: a descriptive study. Online braz j nurs [Internet]. 2016 [acesso em 20 mai 2019];15(1):21-31. Disponível em: http://www.objnursing.uff.br/index.php/nursing/article/view/5298.
The works published in this magazine are subject to the following terms:
1. The Publications Service of the University of Murcia (the publisher) preserves the copyright of the published works, and encourages and allows the reuse of the works under the license for use stated in point 2.
© Servicio de Publicaciones, Universidad de Murcia, 2011 (© Publications Service, University of Murcia, 2011)
2. The works are published in the electronic edition of the journal under Creative Commons Reconocimiento-NoComercial-SinObraDerivada 3.0 España(texto legal) “ a Attribution-NonCommercial-NoDerivatives 3.0 Spain license (legal text)”. They can be copied, used, broadcasted, transmitted and publicly displayed, provided that: i) the authorship and original source of their publication (journal, publisher and URL) are cited; (ii) are not used for commercial purposes; iii) the existence and specifications of this license is mentioned.
3. Conditions of self-archiving. Authors are allowed and encouraged to electronically disseminate the pre-print (pre-reviewed ) and / or post-print (reviewed and accepted for publication) versions of their works prior to publication, as it ensures a wider circulation and dissemination which may lead to a possible increase in its mention and a higher scope among the academic community. RoMEO color: green.