Diseases associated with loneliness in the elderly: a social challenge

Authors

DOI: https://doi.org/10.6018/eglobal.514761
Keywords: Disease, Loneliness, Aged, Aged 80 and over

Abstract

Objective: Identify pathologies in the elderly associated with loneliness.

Methodology: Secondary research, integrative review type, structured according to Crossetti’s consensus.

Results: After applying descriptors and search strategies, a total of 4,011 articles were identified, after applying filters, inclusion, and exclusion criteria, 27 articles were selected; from these articles 17 corresponded to WoS, 9 to BVS and 1 to PubMed.

Conclusions: The association between loneliness and cognitive impairment, decreased physical fitness, Alzheimer's disease and cardiovascular events is highlighted. It is necessary to establish public policies to prepare people for their future aging process.

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Author Biographies

Miguel Valencia-Contrera, Departamento de enfermería, Universidad de Antofagasta. Estudiante Doctorado en Ciencia de Enfermería, Universidad Andrés Bello, Chilke.

Enfermero, Magíster en Enfermería, estudiante de Doctorado en Ciencia de Enfermería, Universidad Andrés Bello, Chile.

Olivia Sanhueza-Alvarado, Facultad de enfermería, Universidad de Concepción.

Doctora en Enfermería, Docente del Postgrado en Enfermería. Universidad de Concepción.

References

Organización Mundial de la Salud (OMS), envejecimiento y salud [Internet]. Ginebra: OMS, 2018 [cited on May 22, 2021]. Available at: https://www.who.int/es/news-room/fact-sheets/detail/envejecimiento-y-salud

Julsing J, Kromhout D, Geleijnse J, Giltay E. Loneliness and All-Cause, Cardiovascular, and Noncardiovascular Mortality in Older Men: The Zutphen Elderly Study.Am JGeriatr Psychiatry. 2016,24(6):475-484. Available at:https://doi.org/10.1016/j.jagp.2016.01.136

Yin J, Lassale C, Steptoe A, Cadar D. Exploring the bidirectional associations between loneliness and cognitive functioning over 10 years: the English longitudinal study of ageing. IntJEpidemiol. 2019,48(6):1937-1948. Available at: https://doi.org/10.1093/ije/dyz085

Zhong B, Chen S, Tu X, Conwell Y. Loneliness and cognitive function in older adults: findings from the Chinese longitudinal healthy longevity survey.JournalsGerontol SerBPsycholSciSocSci. 2016,72(1):120-128. Available at: https://doi.org/10.1093/geronb/gbw037

Van der Velden P, Hyland P, Contino C, von Gaudecker H, Muffels R, Das M. Anxiety and depression symptoms, the recovery from symptoms, and loneliness before and after the COVID-19 outbreak among the general population: Findings from a Dutch population-based longitudinal study. PLOS ONE [Internet]. 2021,16(1):e0245057. Available at: https://pubmed.ncbi.nlm.nih.gov/33411843/

Crossetti M da GO. Revisión integrativa de la investigación en enfermería, el rigor científico que se le exige. RevGaúcha Enferm [Internet]. 2012,33(2):10-11. Available at: https://doi.org/10.1590/S1983-14472012000200002

Park N, Jang Y, Lee B, Chiriboga D. The relation between living alone and depressive symptoms in older Korean Americans: do feelings of loneliness mediate? Aging Ment Health. 2015,21(3):304-312. Available at: https://doi.org/10.1080/13607863.2015.1099035

Han S, Adeyemi O, Wilson R, Leurgans S, Jimenez A, Oullet L, et al. Loneliness in Older Black Adults with Human Immunodeficiency Virus Is Associated with Poorer Cognition. Gerontology. 2017,63(3):253-262. Available at: https://doi.org/10.1159/000455253

Donovan N, Wu Q, Rentz D, Sperling R, Marshall G, Glymour M. Loneliness, depression and cognitive function in older U.S. adults. Int J Geriatr Psychiatry. 2016,32(5):564-573. Available at: https://doi.org/10.1002/gps.4495

Richard A, Rohrmann S, Vandeleur C, Schmid M, Barth J, Eichholzer M. Loneliness is adversely associated with physical and mental health and lifestyle factors: Results from a Swiss national survey. PLOS ONE [Internet]. 2017,12(7):e0181442. Available at: https://doi.org/10.1371/journal.pone.0181442

Olaya B, Domènech-Abella J, Moneta M, Lara E, Caballero F, Rico-Uribe L, et al. All-cause mortality and multimorbidity in older adults: The role of social support and loneliness. Experimental Gerontology. 2017,99:120-126. Available at: https://doi.org/10.1016/j.exger.2017.10.001

Hegeman A, Schutter N, Comijs H, Holwerda T, Dekker J, Stek M, et al. Loneliness and cardiovascular disease and the role of late-life depression. Int J Geriatr Psychiatry [Internet]. 2017,33(1):e65-72. Available at: https://doi.org/10.1002/gps.4716

Kong D, Davitt J, Dong X. Loneliness, Depressive Symptoms, and Cognitive Functioning Among U.S. Chinese Older Adults. GerontolGeriatr Med. 2018,4:1-8. Available at: https://doi.org/10.1177/2333721418778201

Lara E, Caballero F, Rico‐Uribe L, Olaya B, Haro J, Ayuso‐Mateos J et al. Are loneliness and social isolation associated with cognitive decline? Int J Geriatr Psychiatry. 2019,34(11):1613-1622. Available at:https://doi.org/10.1002/gps.5174

Shiovitz-Ezra S, Parag O. Does loneliness ‘get under the skin’? Associations of loneliness with subsequent change in inflammatory and metabolic markers. Aging Ment Health. 2018,23(10):1358-1366. Available at: https://doi.org/10.1080/13607863.2018.1488942

Sundström A, Adolfsson A, Nordin M, Adolfsson R. Loneliness Increases the Risk of All-Cause Dementia and Alzheimer’s Disease. Journals Gerontol SerB. 2019,75(5):919-926. Available at: https://doi.org/10.1093/geronb/gbz139

Hoogendijk E, Smit A, Dam C, Schuster N, Breij S, Holwerda T et al. Frailty Combined with Loneliness or Social Isolation: An Elevated Risk for Mortality in Later Life. J Am Geriatr Soc. 2020,68(11):2587-2593. Available at: https://doi.org/10.1111/jgs.16716

Kraav S, Awoyemi O, Junttila N, Vornanen R, Kauhanen J, Toikko T et al. The effects of loneliness and social isolation on all-cause, injury, cancer, and CVD mortality in a cohort of middle-aged Finnish men. A prospective study. Aging Ment Health. 2021,25(12):2219-2228. Available at: https://doi.org/10.1080/13607863.2020.1830945

McCaffery J, Anderson A, Coday M, Espeland M, Gorin A, Johnson K et al. Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study. J Aging Res [Internet]. 2020,2020(ID7543702):1-8. Available at: https://doi.org/10.1155/2020/7543702

Yu B, Steptoe A, Niu K, Jia X. Social Isolation and Loneliness as Risk Factors for Grip Strength Decline Among Older Women and Men in China. J Am Med Dir Assoc. 2020,21(12):1926-1930. Available at: https://doi.org/10.1016/j.jamda.2020.06.029

Giné-Garriga M, Jerez-Roig J, Coll-Planas L, Skelton D, Inzitari M, Booth J, et al. Is loneliness a predictor of the modern geriatric giants? Analysis from the survey of health, ageing, and retirement in Europe. Maturitas. 2021,144:93-101. Available at: https://doi.org/10.1016/j.maturitas.2020.11.010

Canli T, Yu L, Yu X, Zhao H, Fleischman D, Wilson R, et al. Loneliness 5 years ante-mortem is associated with disease-related differential gene expression in postmortem dorsolateral prefrontal cortex. Transl Psychiatry. 2018,8(1):1-9. Available at: https://doi.org/10.1038/s41398-017-0086-2

Yu J, Lam C, Lee T. Perceived loneliness among older adults with mild cognitive impairment. Int Psychogeriatrics. 2016,28(10):1681-1685. Available at: https://doi.org/10.1017/S1041610216000430

Donovan NJ, Okereke OI, Vannini P, Amariglio RE, Rentz DM, Marshall GA, et al. Association of higher cortical amyloid burden with loneliness in cognitively normal older adults. JAMA Psychiatry. 2016,73(12):1230–1237. Available at:https://doi.org/10.1001/jamapsychiatry.2016.2657

Gale C, Westbury L, Cooper C. Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing. Age Ageing. 2017,47(3):392-397. Available at: https://doi.org/10.1093/ageing/afx188

Valtorta N, Kanaan M, Gilbody S, Hanratty B. Loneliness, social isolation and risk of cardiovascular disease in the English Longitudinal Study of Ageing. Eur J Prev Cardiol. 2018,25(13):1387-1396. Available at: https://doi.org/10.1177/2047487318792696

Wilson S, Woody A, Padin A, Lin J, Malarkey W, Kiecolt-Glaser J. Loneliness and Telomere Length: Immune and Parasympathetic Function in Associations With Accelerated Aging. Ann Behav Med. 2018,53(6):541-550. Available at: https://doi.org/10.1093/abm/kay064

Kobos E, Szewczyk A, Świątkowska T, Kryczka T, Sienkiewicz Z. Relationship between loneliness and blood glucose control in diabetes. BMC Public Health. 2020,20(1):1140. Available at: https://doi.org/10.1186/s12889-020-09241-z

Philip K, Polkey M, Hopkinson N, Steptoe A, Fancourt D. Social isolation, loneliness and physical performance in older-adults: fixed effects analyses of a cohort study. Sci Rep. 2020,10(1):13908. Available at: https://doi.org/10.1038/s41598-020-70483-3

Novak M, Waern M, Johansson L, Zettergren A, Ryden L, Wetterberg H, et al. Cardiovascular and all-cause mortality attributable to loneliness in older Swedish men and women. BMC Geriatr. 2020,20(1):201. Available at: https://doi.org/10.1186/s12877-020-01603-x

Published
03-01-2023
How to Cite
[1]
Valencia-Contrera, M. and Sanhueza-Alvarado, O. 2023. Diseases associated with loneliness in the elderly: a social challenge. Global Nursing. 22, 1 (Jan. 2023), 642–668. DOI:https://doi.org/10.6018/eglobal.514761.
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