Evaluation of a peripheral vein for intravenous chemotherapy: a prospective observational study

Authors

  • Carolina de Sousa Custódio Oncology Department, University Hospital of Brasília, Brasília, DF, Brazil
  • Marcia Aparecida Ciol Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle, WA
  • Stefane Laura Nunes de Sousa Base Hospital of the Federal District, Brasília, DF, Brazil
  • Giovana Paula Resende Simino School of Nursing, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
  • Paula Elaine Diniz dos Reis Nursing Department, School of Health Sciences, University of Brasília, Brasília, DF, Brazil
  • Christiane Inocencio Vasques Facultad de Ciencias de la Salud, Universidad de Brasilia, Brasilia, DF, Brasil
DOI: https://doi.org/10.6018/eglobal.485851
Keywords: antineoplastic agents, breast neoplasms, infusions, intravenous, nursing care

Abstract

This study aimed to assess over time alterations of a peripheral vein used for chemotherapy infusion in patients with breast cancer. It is a prospective observational study which included patients who were scheduled to receive peripheral infusion of chemotherapy. These patients had the first peripheral vein used for infusion evaluated in five moments: before the venipuncture, after device removal at the end of the first chemotherapy infusion, and on days 21, 42, and 63 after the first infusion. The primary outcome was the caliber of the vein, measured in millimeters with a Veinlite LEDX® transilluminator and a tape measure. Fifty-nine women receiving doxorubicin and docetaxel for the first time were enrolled to the study. The caliber size varied from 2 to 4 millimeters at baseline, and decreased overtime. During the follow-up period, peripheral veins of 35 women (59.3%) were measured at 0 mm at day 63. The remaining 24 women (40.7%) had some recovery, but for 15 of them (62.5%) the vein became a palpable cord. The feasibility of using a peripheral vein to perform chemotherapy decreased as the treatment progresses.

Downloads

Download data is not yet available.

Author Biographies

Carolina de Sousa Custódio, Oncology Department, University Hospital of Brasília, Brasília, DF, Brazil

MSc, RN

Marcia Aparecida Ciol, Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle, WA

PhD, Research Professor

Stefane Laura Nunes de Sousa, Base Hospital of the Federal District, Brasília, DF, Brazil

RN

Giovana Paula Resende Simino, School of Nursing, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil

PhD, RN, Adjunct Professor  

Paula Elaine Diniz dos Reis, Nursing Department, School of Health Sciences, University of Brasília, Brasília, DF, Brazil

PhD, RN, Associate Professor

References

Bertoglio S, Boxtel TV, Goossens GA, Dougherty L, Furtwangle R, Lennan E, et al. Mejora de los resultados del acceso vascular periférico corto en la administración de oncología y quimioterapia. J Vasc Access. 2017;18(2), 89-96. Disponible en: https://doi.org/10.5301%2Fjva.5000668

Reis PED, Rodrigues CC, Vasques CI, Carvalho EC. Efectos adversos por Drogas quimioterápicas identificados en el sitio de infusión intravenosa periférica. Ciencia y Enfermeria. 2008;14(2), 55-64.

McGowan D, Wood S. Desarrollando una herramienta de evaluación venosa en la administración de quimioterapia intravenosa. Br J Nurs. 2008;17(3), 158-164. Disponible en: https://doi.org/10.12968/bjon.2008.17.3.28404

Cole T. Riesgos y beneficios del uso de agujas en pacientes después de una cirugía de ganglios axilares. Br J Nurs. 2006;15(18), 969-979. Disponible en: https://doi.org/10.12968/bjon.2006.15.18.22020

García-Mata J, García-Palomo A, Calvo L, Mel R, Cruz JJ, Ramos M. Estudio de fase II de doxorrubicina densa en dosis y docetaxel como quimioterapia neoadyuvante con apoyo de G-CSF en pacientes con cáncer de mama grande o localmente avanzado. Clin Transl Oncol. 2008;10(11), 739-744. Disponible en: https://doi.org/10.1007/s12094-008-0280-z

Montañez-Valverde RA, Hurtado-de-Mendoza D, Loaiza-Bonilla A. Cardiotoxicidad: Miocardio o Endotelio. Cureus. 2018;10(7), e2994. Disponible en: https://doi.org/10.7759/cureus.2994

Cameron AC, Touyz RM, Lang NN. Complicaciones vasculares de la quimioterapia contra el cáncer. Can J Cardiol. 2016;32(7), 852-862. Disponible en: https://doi.org/10.1016/j.cjca.2015.12.023

Soultati A, Mountzios G, Avgerinou C, Papaxoinis G, Pectasides D, Dimopoulos MA, et al. Toxicidad vascular endotelial por agentes quimioterapéuticos: evidencia preclínica e implicaciones clínicas. Cancer Treat Rev. 2012;38(5), 473-483. Disponible en: https://doi.org/10.1016/j.ctrv.2011.09.002

Wojcik T, Szczesny E, Chlopicki S. Efectos perjudiciales de la quimioterapia y otros fármacos en el endotelio: un llamado a la elaboración de perfiles de toxicidad endotelial. Pharmacol Rep. 2015;67(4), 811-817.

Mestre G, Berbel C, Tortajada P, Alarcia M, Coca R, Fernández MM, et al. Intervención multifacética exitosa dirigida a reducir los eventos adversos relacionados con el catéter venoso periférico corto: un estudio de cohorte cuasi experimental. Am J Infect Control. 2013; 41(6), 520-526. Disponible en: https://doi.org/10.1016/j.ajic.2012.07.014

Alexandrou E, Ray-Barruel G, Carr PJ, Frost S, Inwood S, Higgins N, et al. Prevalencia internacional del uso de catéteres intravenosos periféricos. J Hosp Med. 2015; 10(8), 530-533. Disponible en: https://doi.org/10.1002/jhm.2389

Atay S, Sen S, Cukurlu D. Cateterismo venoso periférico relacionado con la flebitis y los factores de riesgo asociados. Niger J Clin Pract. 2018; 21(7), 827-831. Disponible en: https://doi.org/10.4103/njcp.njcp_337_17

Schulmeister L. Manejo de extravasación: actualización clínica. Semin Oncol Nurs. 2011; 27(1), 82-90. Disponible en: https://doi.org/10.1016/j.soncn.2010.11.010

Sakaida E, Sekine I, Iwasawa S, Kurimoto R, Uehara T, Ooka Y, et al. Incidencia, factores de riesgo y resultados del tratamiento de la extravasación de agentes citotóxicos en una clínica de quimioterapia para pacientes ambulatorios. Jpn J Clin Oncol. 2014; 44(2), 168-171. Disponible en: https://doi.org/10.1093/jjco/hyt186

Gallieni M, Pittiruti M, Biffi R. Acceso vascular en pacientes oncológicos. CA: Cancer J Clin. 2008; 58(6), 323-346. Disponible en: https://doi.org/10.3322/ca.2008.0015

Gorski L, Hadaway L, Hagle ME, McGoldrick M, Orr M, Doellman D. Estándares de práctica de la terapia de infusión. J Infus Nurs, 2016; 39(1S), 1-169. Disponible en: https://doi.org/10.1097/nhh.0000000000000481

Published
01-04-2022
How to Cite
[1]
Custódio, C. de S. et al. 2022. Evaluation of a peripheral vein for intravenous chemotherapy: a prospective observational study . Global Nursing. 21, 2 (Apr. 2022), 28–45. DOI:https://doi.org/10.6018/eglobal.485851.
Issue
Section
ORIGINAL RESEARCH