(MORPHOLOGICAL ALTERATIONS OF THE RETICULAR ZONE CELLS OF THE ADRENAL GLANDS OF MALE WISTAR RATS TREATED WITH OESTRADIOL AN TRENBOLONE ACETATE)
Abstract
structural and ultrastructural modifications in adrenal parenchyme of rats treated with oestradiol and trenbolone acetate have been studied. Twenty-five male Wistar rats were used as material of study distributed in two groups: one of 28 animals divided in seven lots of four animals each, and other of seven animals used as witness. In every rat of the first group a table containing 2,5 mg of oestradiol and 17,2 mg. of trenbolone acetate was implanted subcutaneously bhind the ear. Both groups were sacrified on the first, third, fifth, seventh, fifteenth, thirtieth and sixtieth day postimplantation. Cellular elements in the reticular zone of adrenal glands present a mitochondrial hypertrphy characterized in the second lot by a population with size differences. Lots third to fifth show such hypertrophy more evident, with a homogeneity in their population. In the last two lots in addition to an increase in the smooth endoplasmic reticle, anabolizant steroids ans sexual hormone synthesis are increased.Downloads
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