ADENOHYPOPHYSIS MORPHOLOGICAL ALTERATIONS OF MALE WISTAR RATS TREATED WITH OESTRADIOL AND TRENBOLONE ACETATE
Abstract
Structural and ultrastructural modifications in adenohypophysis parenchume of rats treated with oestradiol and trenbolone acetate have been studied. Thirty-five male Wistar rats were used as material of study distributed in two groups: one of 28 animals divided in seven lots of four animals each, and other of seven animals used as witness. In every ral of the first group a tablet containing 2'5 mg of oestradiol and 17'5 mg of trenbolone acelate was implanted subcutaneously behind the ear. Both groups were sacrified on the first, third, fifth, seventh, fifteenth, thirtieth and sixtieth day postimplatation. Most significative modifications found in adenohypohysis gland were a decrease in number of TSH cells, and an increase in the LTH, LH. FSH ones, the first two (LTH and LH) being the ones that most suffered the increase, for the FSH ones only increased in the first day of implantation. ACTH and STH cells did not suffer any modification.Downloads
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