Histopathological and immunophenotypical characterization of a combined melanoma and mucoepidermoid carcinoma in a dog

Authors

  • C. M. Martínez Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia
  • A. J. Buendía Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia
  • J. Sánchez Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia
  • M. Vilafranca Histovet S.L., Stz. Quirze del Vallés, Barcelona, Spain.
  • J. Altimira Histovet S.L., Stz. Quirze del Vallés, Barcelona, Spain.
  • G. Ramírez Histovet S.L., Stz. Quirze del Vallés, Barcelona, Spain.
  • B. García Histovet S.L., Stz. Quirze del Vallés, Barcelona, Spain.
  • J. A. Navarro Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia
Keywords: canine, histopathology, immunohistochemistry, carcinoma, melanoma

Abstract

The present paper reports the fi rst case of a canine high-grade (low differentiated) mucoepidermoid carcinoma, in which malignant proliferation of melanocytes has been detected. The tumoral mass was located in the lower neck, pressing against the 7th cervical vertebral body in an aged dog of mixed breed. No macroscopic signs of skin or oral melanoma or carcinoma were detected elsewhere. The microscopic examination showed close intermingling of the two components. Melanocytic proliferation rarely occurs accompanied by the colonization of nonmelanocytic tumors, and the cause of such proliferation remains unclear. In human pathology, several reports of pigmented mucoepidermoid carcinomas have been described, and in all cases the proliferation of the melanocytic component was considered as hyperplastic, and no sign of malignant proliferation was detected. However, neither in human nor in veterinary pathology has a case of intermingled melanoma and mucoepidermoid carcinoma been described.

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How to Cite
Martínez, C. M., Buendía, A. J., Sánchez, J., Vilafranca, M., Altimira, J., Ramírez, G., … Navarro, J. A. (2009). Histopathological and immunophenotypical characterization of a combined melanoma and mucoepidermoid carcinoma in a dog. Anales de Veterinaria de Murcia, 25, 135–142. Retrieved from https://revistas.um.es/analesvet/article/view/100261
Issue
Vol. 25 (2009)
Section
Trabajos Fin de Grado/Fin de Máster

 

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