Influence of Body Mass Index on Assisted Reproductive Techniques

Authors

DOI: https://doi.org/10.6018/eglobal.555361
Keywords: Body mass index, Treatment Outcome, Reproductive Techniques Assisted

Abstract

Objective. To analyze the relationship between the Body Mass Index in women and the results obtained in assisted reproductive techniques.
Methods. A non-experimental, cross-sectional, descriptive and correlational design was carried out through an analysis of secondary data in several assisted reproduction clinics from Spain. 3,273 medical records of women undergoing In Vitro Fertilization between 2015 and 2018 were analyzed. Data on affiliation and treatment initiation, anthropometric data, personal history, current diseases, primary and secondary infertility, as well as the reference parameters to the results after the assisted reproduction treatment were collected. The statistical analysis was performed using SPSS v19.0 software.
Results. A total of 798 women (24.42%) had a BMI values ≥ 25. The overweight women achieved a lower number of oocytes retrieved and fertilized, as well as fewer embryos obtained. The women with normal weight achieved a lower number of mature oocytes and those with low weight had a lower fertilization rate.
Conclusions. It has been found that the results obtained in assisted reproductive techniques are related to women's Body Mass Index.

 

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References

Damario M. General Aspects of fertility and Infertility. Hertfordshire, United Kingdom: Editorial Human Press; 2014. Doi: https://doi.org/10.1016/j.rbmo.2019.10.008.

Viera-Molina M, & Guerra-Martín MD. Análisis de la eficacia de las técnicas de reproducción asistida: una revisión sistemática. An Sist Sanit Navar 2018; 41 (1): 107-116. Doi: https://dx.doi.org/10.23938/assn.0254

Bonfill X, & Urrutia G. Análisis y generación de evidencias en reproducción medicamente asistida [Tesis Doctoral]. España, Universidad Autónoma de Barcelona; 2015. https://ddd.uab.cat/pub/tesis/2015/hdl_10803_322783/rbgv1de1.pdf

Matorras WR. La infertilidad en España: Situación actual y perspectivas. Madrid: Editorial Imago Concept & Image Development; 2011. https://www.sefertilidad.net/docs/biblioteca/libros/libroBlanco.pdf

Matorras R, & Hernández J. Estudio y tratamiento de la pareja estéril: Recomendaciones de la Sociedad Española de Fertilidad. Madrid: Adalia; 2007. https://www.sefertilidad.net/docs/biblioteca/recomendaciones/completo.pdf

Brewer CJ, & Balen A. The adverse effects of obesity on conception and implantation. Reproduction 2010;140 (3): 347–364. Doi: https://doi.org/10.1530/REP-09-0568

Levens E, & Skarulis M. Assessing the role of endometrial alteration among obese patients undergoing assisted reproduction. Fertility and sterility 2008; 89 (6):1606–1608. Doi: https://doi.org/10.1016/j.fertnstert.2007.03.079

Luke B, Brown M, Stern J, Missmer S, Fujimoto V, & Leach R. Female obesity adversely affects assisted reproductive technology (ART) pregnancy and live birth rates. Human Reproduction 2011; 26 (1): 245-252. Doi: https://doi.org/10.1093/humrep/deq306

Leary C, Leese HJ, & Sturmey RG. Human embryos from overweight and obese women display phenotypic and metabolic abnormalities. Human Reproduction 2015; 30 (1): 122-132. Doi: https://doi.org/10.1093/humrep/deu276

Ozekinci M, Seven A, Olgan S, Sakinci M, Keskin U, Akar ME, Ceyhan ST, Ergun A. Does obesity have detrimental effects on IVF treatment outcomes? BMC Women’s Health 2015; 19 (15): 61. Doi: https://doi.org/10.1186/s12905-015-0223-0

Organización Mundial de la Salud. Obesity: preventing and managing the global epidemic [Internet]. Geneva; 2000. [Citado 03/2020]. Recuperado a partir de: https://apps.who.int/iris/handle/10665/42330

Zegers-Hochschild F, Crosby J, Musri C, Souza M, Martinez G, Silva A, Mojarra J, Masoli D, & Posada N. Assisted reproductive techniques in Latin America: The Latin American Registry, 2017. JBRA Assisted Reproduction 2020; 24 (3): 362-378. Doi: https://doi.org/10.5935/1518-0557.20200029

Chavarro J, Ehrlich S, Colaci D, Wright D, Toth T, Petrozza JC, & Hauser R. Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction. Fertility and Sterility 2012; 98 (1): 109–116. Doi: https://doi.org/10.1016/j.fertnstert.2012.04.012

Pisarska MD, Chan JL, Lawrenson K, Gonzalez TL, & Wang ET. Genetics and Epigenetics of Infertility and Treatments on Outcomes. The Journal of clinical endocrinology and metabolism 2019; 104 (6): 1871–1886. Doi: https://doi.org/10.1210/jc.2018-01869

Liu Y, & Zhang W. Association between body mass index and endometriosis risk: a meta-analysis. Oncotarget 2017; 8 (29): 46928–46936. Doi: https://doi.org/10.18632/oncotarget.14916

Cui N, Wang H, Wang W, Zhang J, Xu Y, Jiang L, Yang A, & Hao G. Impact of Body Mass Index on Outcomes of In Vitro Fertilization/Intracytoplasmic Sperm Injection Among Polycystic Ovarian Syndrome Patients. Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology 2016; 39 (5): 1723–1734. Doi: https://doi.org/10.1159/000447873

McCormick B, Thomas M, Maxwell R., Williams D, & Aubuchon M. Effects of polycystic ovarian syndrome on in vitro fertilization embryo transfer outcomes are influenced by body mass index. Fertility and Sterility 2008; 90 (6): 2304-2309. Doi: https://doi.org/10.1016/j.fertnstert.2007.10.077

Marquard KL, Stephens SM, Jungheim ES, Ratts VS, Odem RR, Lanzendorf S, & Moley KH. Polycystic ovary syndrome and maternal obesity affect oocyte size in in vitro fertilization/intracytoplasmic sperm injection cycles. Fertility and sterility 2011; 95(6): 2146–2149.e1. Doi: https://doi.org/10.1016/j.fertnstert.2010.10.026

Chiaffarino F, Parazzini F, Vecchia C, Chatenoud L, Di Cintio E, & Marsico S. Diet and uterine myomas. Obstet Gynecol 1999; 94 (3): 395-398. Doi: 10.1016/s0029-7844(99)00305-1

Sparic P, Mirkovic L, Malvasi A, & Tinelli A. Epidemiology of Uterine Myomas: A Review. Fertility & Sterility 2016; 9 (4): 424-435. Doi: 10.22074/IJFS.2016.4599

Lethaby AE, & Vollenhoven BJ. Fibroids (uterine myomatosis, leiomyomas). BMJ clinical evidence 2007: 0814.

Parker W. Etiology, symptomatology, and diagnosis of uterine myomas. Fertility & Sterility 2007; 87 (4): 725-736. Doi: https://doi.org/10.1016/j.fertnstert.2007.01.093

Benksim A, Elkhoudri N, Ait Addi R, Baali A, & Cherkaoui M. Difference between Primary and Secondary Infertility in Morocco: Frequencies and Associated Factors. Royan Institute International Journal of Fertility and Sterility 2017; 12 (2): 141-146. Doi: 10.22074/ijfs.2018.5188

Musoles F, Castillo JC, Raga F, Caballero O, Machado LE, Pérez-Panades J, Bonilla F, Dolz M. Valores de hormona antimülleriana (HAM) y recuento de folículos antrales (RFA) en casos con fallo reproductivo previo. Procesos de obstetricia y ginecología 2012; 55 (1): 8-14. Doi: https://doi.org/10.1016/j.pog.2011.08.012

Yang W, Yang R, Lin M, Yang Y, Song X, Zhang J, et al. Body mass index and basal androstenedione are independent risk factors for miscarriage in polycystic ovary syndrome. Reprod Biol Endocrinol 2018; 16:119. Doi: https://doi.org/10.1186/s12958-018-0438-7

Beydoun HA, Stadtmauer L, Beydoun MA, Russell H, Zhao Y, Oehninger S. Polycystic ovary syndrome, body mass index and outcomes of assisted reproductive technologies. Reproductive BioMedicine Online 2009; 18 (6): 856-863. Doi: 10.1016/s1472-6483(10)60037-5.

Orvieto R, Meltcer S, Nahum R, Rabinson J, Anteby EY, Ashkenazi J. The influence of body mass index on in vitro fertilization outcome. International Journal of Gynecology & Obstetrics 2009; 104 (1): 53-55. Doi: https://doi.org/10.1016/j.ijgo.2008.08.012

Sarais V, Pagliardini L, Rebonato G, Papaleo E, Candiani M, Vigano P. A Comprehensive Analysis of Body Mass Index Effect on in Vitro Fertilization Outcomes. Nutrients 2016; 8: 109. Doi: https://doi.org/10.3390/nu8030109

Loveland JB, McClamrock HD, Malinow AM, Sharara FI. Increased Body Mass Index Has a Deleterious Effect on In Vitro Fertilization Outcome. Journal of Assisted Reproduction and Genetics 2001; 18 (7): 382-386. Doi: https://doi.org/10.1023/A:1016622506479

Munares-García O, Gómez-Guizado G, Barboza-Del Carpio J, Sánchez-Abanto J. Limitaciones del análisis secundario de bases de datos - Réplica [carta]. Rev Peru Med Exp Salud Publica 2013; 30 (1):152-3.

Published
01-07-2023
How to Cite
[1]
Viera Molina, M. et al. 2023. Influence of Body Mass Index on Assisted Reproductive Techniques. Global Nursing. 22, 3 (Jul. 2023), 46–67. DOI:https://doi.org/10.6018/eglobal.555361.
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ORIGINAL RESEARCH