Quality of life of patients with Crohn's disease

Authors

  • Antonia Mauryane Lopes UNIVERSIDADE FEDERAL DO PIAUÍ
  • Laís Norberta Bezerra de Moura Hospital Universitario do Piauí-Teresina, Piauí.
  • Raylane da Silva Machado Universidade Federal do Piauí–Teresina, Piauí.
  • Grazielle Roberta Freitas da Silva Universidade Federal do Piauí–Teresina, Piauí.
DOI: https://doi.org/10.6018/eglobal.16.3.266341
Keywords: Quality of life, Crohn's disease, Nursing

Supporting Agencies

  • HOSPITAL UNIVERSITARIO DO PIAUÍ

Abstract

Objective: To assess the quality of life of Crohn's disease patients treated at the clinic of the University Hospital from Piauí.
Methods: Exploratory and cross-sectional study in the University Hospital of Piauí  - Brazil, from July  to December 2015, with a sample of 52 Crohn's disease patients. A form was applied to characterize the sociodemographic and clinical profile, and the instrument "Inflammatory Bowel Disease Questionnaire" was used to assess the quality of life.
Results: Most participants were females, adults, self-declared brown-skinned, married, with family income of two minimum wages, with high school education and non-smokers and alcohol drinkers. Diagnostic time was longer than five years, and patients are partly in remission of the disease. Few patients had marked weight loss, diarrhea and abdominal pain in the last three months. Patients had been hospitalized due to Crohn's disease, a quarter of them had undergone surgical resection of the bowel and had had complications such as fistulas, more often. As drug treatment, association of immunomodulators and aziotioprina was used. Most had performed laboratory tests for control, followed by colonoscopy and they had never abandoned treatment. Patients presented regular quality of life and the response "never" was the most scored in the instrument. Quality of life was regular in the domains of systemic symptoms, emotional and social aspects, and in the intestinal symptoms, it was satisfactory with an average 56.15.
Conclusion: Patients with Crohn's disease have a regular quality of life.

Downloads

Download data is not yet available.

Author Biographies

Laís Norberta Bezerra de Moura, Hospital Universitario do Piauí-Teresina, Piauí.

Enfermera. Máster en Ciencias de la Salud.

Raylane da Silva Machado, Universidade Federal do Piauí–Teresina, Piauí.

Enfermeira.

Grazielle Roberta Freitas da Silva, Universidade Federal do Piauí–Teresina, Piauí.

Doutora em Enfermagem

References

.Ministério da Saúde. Secretaria de Assistência a Saúde. Protocolo clínico e diretrizes terapêuticas – Doença de Crohn. Brasília: Ministério da saúde, 2014. Portaria n.966, de 02 de Novembro de 2004. DOU Brasilia, DF, n.214, seção I, p. 77-85, 5 de Nov. 2014.

Freeman HJ. Long-term natural history of Crohn's disease. World J Gastroenterol. 2009; 15(11):1315-8.

World Gastroenterology Organization Practice Guidelines. Doença Inflamatória Intestinal: uma perspectiva global. 2009.1(1)

Gaburri PD, Chebli JM, Castro LE, Ferreira JO, Lopes MH, Ribeiro AM et al. Epidemiology, clinical features and clinical course of Crohn's disease: a study of 60 cases. Arq Gastroenterol. 1998; 35 (4): 240-6.

Victoria CR., Sassak LV, Nunes HR. Incidence and prevalence rates of inflammatory bowel diseases, in Midwestern of. Arq Gastroenterol.2009; 46 (1):20-5.

Word Health Organization (who). The Word Health Organization Quality of Life Assessement (WHOQOL): position paper from the Word Health Organization. Soc. Sci. Med.1998

Almeida MAB. Qualidade de vida: definição, conceitos e interfaces com outras á reas de pesquisa / São Paulo: Escola de Artes, Ciências e Humanidades. EACH/USP.2012.142.

Pontes RMA, Miszputen SJ, Ferreira-Filho OF, Miranda CFMB. Qualidade de vida em pacientes portadores de doença inflamatória intestinal: tradução para o português e validação do questionário "Inflammatory Bowel Disease Questionnaire" (IBDQ). Arq. Gastroenterol. 2004; 41(2): 137-143.

Meyer ALM. Qualidade de vida no seguimento tardio de doentes portadores de Retocolite ulcerativa submetidos a proctocolectomia com conservação esfincteriana há mais de dez anos. São Paulo. Dissertação. (Mestrado). Universidade Federal de São Paulo. 2009.

Tilio MSG, Ariasb L, Camargob GM , Oliveira PSP, Panzettib N V, Ayrizonob M L S et al. Quality of life in patients with ileal pouch for ulcerative colitis. J coloproctol. 2013; 33(3):113–117114.

Graff LA, Walker JR, Bernstein CN. Depression and anxiety in inflammatory bowel disease: a review of comorbidity and management. Inflamm Bowel Dis 2009; 15(7): 1105-18.

Michael J R, MD, MSCI; Ashish D MBBS, MSPH, Shehzad A. Saeed, MD. Inflammatory bowel disease in children and adolescentes. JAMA Pediatr. 2015; 169(11): 1053-1060.

Moradkhani A, Beckman LJ, Tabibian JH. Health-related quality of life in inflammatory bowel disease: psychosocial, clinical, socioeconomic, and demographic predictors. J Crohns Colitis.2013;7 (1):467-73.

Gandhi S, Jedel S, Hood M M, Mutlu E, Swanson G, Keshavaezian A. The relationship between coping, health competence and patient participation among patients with inactive inflammatory bowel disease. J. Crohn's Colitis. 2014; 8 (5):401-408.

Magalhães JD, Francisca DC, Pedro BC, João FM, Silvia L, Maria JM, José C. Disability in inflammatory bowel disease: translation to portuguese and validation of the Inflammatory Bowel Disease – Disability Score. GE Port. J. Gastroenterol. 2015; 22 (1): 4-14.

Zelinkova Z, Der Woude CJ, Gender and. Inflammatory Bowel Disease. J. Clín. Cell Immunol. 2014; 5(4): 245.

Faria LC, Ferrari MLA, Cunha AS. Aspectos clínicos da doença de Crohn em um centro de referência para doenças intestinais. GED Gastroenterol Endosc Dig. 2004 ; 23(4):151-64.

Casellas F, Arenas JI, Baudet JS, Fábregas S, García N, Gelabert J, et al. Impairment of health-related quality of life in patients with inflammatory bowel disease: a Spanish multicenter study. Inflamm Bowel Dis. 2005; 11(5): 488-96.

Coelho MID. Qualidade de Vida e Doença Inflamatória Intestinal. Covilhã. Dissertação (Mestrado Integrado em Medicina). Universidade da Beira Interior - Faculdade ciências da Saúde.2010.

Taft TH, Keefer L, Artz C, Bratten J, Jones MP. Perceptions of illness stigma in patients with inflammatory bowel disease and irritable bowel syndrome. Qual. Life Res. 2011; 20 (9): 1391-1399.

Peruzzi EP, Soares HF, Barros GG, Rego RGG, Zaltman CEC Siqueira EC.Análise descritiva dos perfis social, clínico, laboratorial e antropométrico de pacientes com doenças inflamatórias intestinais, internados no Hospital Universitário Clementino Fraga Filho, Rio de Janeiro. Arq. Gastroenterol. 2007; 2(4):332-339.

Feagan BG, Bala M, Yan S, Olson, Hanauer S. Unemployment and disability in patients with moderately to severely active Crohn’s disease. J. Clin. Gastroenterol. 2005; 39(3)390-500.

Israeli, E, Graff AL, Clara I, Walker R J, Mix L M, Targownik LE, Beenstein C N. Low prevalence of disability among patients with inflammato bowel diseases a decade after diagnosis. Clín. Gastroenterol. Hepatol. 2014; 12(8): 1330-1337.

Leowardi C, Hinz U, Tariverdian M, Kienle P, Herfarth C, Ulrich A, Kadmon M. Long-term outcome 10 years or more after restorative proctocolectomy and ileal pouch-anal anastomosis in patients with ulcerative colitis. Langenbecks Arch Surg. 2010; 395 (1):49-56.

Hahnloser D, Pemberton JH, Wolff BG, Larson DR, Crownhart BS, Dozois RR. Results at up to 20 years after ileal pouch-anal anastomosis for chronic ulcerative colitis. Br J Surg. 2007; 94 (3):333-40.

Campos MOB, Cavalcante TB. Smoking: etiologic factor for Crohn's disease. Rev Enferm UFPI. 2012; 1(3):201-4.

Martins Jr EV, Araújo IS, Atallah AN, Miszputen SJ. Tabagismo e doença inflamatória intestinal: estudo epidemiológico caso-controle. Arq Gastroenterol. 1996; 33(2): 654-657.

Bielefeldt K, Davis B, Binion DG. Pain and inflammatory bowel disease. Inflamm Bowel Dis. 2009; 15(5): 778-88.

Kuriyama M, Kato J, Kuwaki K et al. Clinical factors that impair healthrelated quality of life in ulcerative colitis patients vary with the disease duration. Eur J Gastroenterol Hepatol. July 2008; 20(7): 634-41.

Burisch J, Weimers P, Pedersen N, Cukovic-Cavka S, Vucelic B, Kaimakliotis I, et al. Health-related quality of life improves during one year of medical na surgical treatment in a European population-based inception cohort of patientmwith inflammatory bowel disease--an ECCO- Epi Com study. J Crohns Colitis.2014;8(9):1030-42

Mc Dermott E, Keegan D, Byrne K, Doherty GA, Mulcahy HE. The Short Health Scale: A valid and reliable measure of health related quality of life in English speaking inflammatory bowel disease patients. J Crohns Colitis. 2012; 21 (4):123-32.

Tilio M S G. Análise da qualidade de vida pós-operatória em pacientes com reservatório ileal por retocolite ulcerativa. Campinas-SP. Dissertação [Mestrado] .Universidade Estadual de Campinas.2013. [ acesso em 04 dezembro2015]. Disponível emhttp://www.bibliotecadigital.unicamp.br/document/?code=000906635

Almeida, MG; Kiss, DR; Teixeira, MG, Habr - Gama, Angelita. Quality of life of long follow-up patients submitted to proctocolectomy with ileal pouch. Rev Bras colo- proctol. 2000;20(3):145-52.

Schnitzler F, Fidder H, Ferrante M. Mucosal healing predicts long-term outcome for maintenance therapy with infliximab in Crohn’s disease. Inflamm Bowel Dis.2009; 15(9) 1295–301.

Hanauer SB, Feagan BG, Lichtenstein GR, Mayer LF, Schenreiber S, Colombel et al. Maintenance infliximab for Crohn`s disease: the ACCENT I randomised trial. Lancet. 2002; 359: 1541-1549.

Silva, ICL. Qualidade de vida relacionada à saúde em pacientes acometidos por doença inflamatória intestinal tratados com terapia biológica. Dissertação [Mestrado] Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina de Botucatu, 2015. [Acesso em 01 dezembro2015]. Disponível em: http://repositorio.unesp.br/handle/11449/128144.

Santos CH M. Comparison between infliximab and adalimumab in the treatment of perianal fistulas in Crohn's disease. J. Coloproctol. 2014:34(3): 154-158.

Published
28-06-2017
How to Cite
[1]
Lopes, A.M. et al. 2017. Quality of life of patients with Crohn’s disease. Global Nursing. 16, 3 (Jun. 2017), 321–368. DOI:https://doi.org/10.6018/eglobal.16.3.266341.
Issue
Section
ORIGINAL RESEARCH