Efecto antidiabético de Atriplex halimus en tratamiento. corto. largo plazo contra la diabetes inducida por estreptozocina

Autores/as

  • Elaid Bounouar university of Abd el hamid ibn badiss of Mostaganem
  • Fatiha MISSOUN UNIVERSITY ABD EL HAMID IBN BADISS MOSTAGANEM
  • Nesrine Ouda Amari university of Abd el hamid ibn badiss of Mostaganem
  • Fatima Zohra Belabaci university of Abd el hamid ibn badiss of Mostaganem
  • Senia Belabaci university of Abd el hamid ibn badiss of Mostaganem
  • Fatima Zohra Sekkal
  • Noureddine Djebli university of Abd el hamid ibn badiss of Mostaganem
DOI: https://doi.org/10.6018/analesbio.44.03
Palabras clave: Atriplex halimus L., Sp.Pl. 2: 1052 (1753), diabetes, fitoquímicos, estreptozotocina, glucemia.

Resumen

El objetivo fue evaluar la actividad antidiabética de hojas de Atriplex halimus en ratas diabéticas modelo. Para evaluar se utilizó la glicemia, pérdida de peso, volumen de consumo de agua, parámetros bioquímicos. estudio histológico. Las investigaciones fitoquímicas indican la presencia de flavonoides, taninos, saponinas, mucílagos, glucósidos. proteínas. Los resultados muestran que el tratamiento con extracto acuoso de A. halimus presenta reducción significativa de los niveles de glucosa en sangre en ratas de los grupos D100. D200, en comparación con el grupo diabético,. protege. las ratas de complicaciones diabéticas. El estudio histológico del páncreas lo confirman por la mejora en los islotes de Langerhans de rata tratada con este extracto vegetal. Atriplex halimus parece ser una planta prometedora para futuros ensayos preclínicos. clínicos en la diabetes de tipo 1.

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Biografía del autor/a

Elaid Bounouar , university of Abd el hamid ibn badiss of Mostaganem

Laboratory  of Pharmacognosy and Api-Phytotherapy, University of Mostaganem (UMAB), Mostaganem 27000, Algeria. 

Nesrine Ouda Amari, university of Abd el hamid ibn badiss of Mostaganem

Laboratory  of Pharmacognosy and Api-Phytotherapy, University of Mostaganem (UMAB), Mostaganem 27000, Algeria.

Fatima Zohra Sekkal

Laboratory of biodiversity and conservation of water and soil ,University of Mostaganem (UMAB), Mostaganem 27000, Algeria

Noureddine Djebli , university of Abd el hamid ibn badiss of Mostaganem

Laboratory  of Pharmacognosy and Api-Phytotherapy, University of Mostaganem (UMAB), Mostaganem 27000, Algeria

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Publicado
10-05-2022
Cómo citar
Bounouar , E. ., MISSOUN, F., Amari, . N. O. ., Belabaci, F. Z., Belabaci , S. ., Sekkal , F. Z. ., & Djebli , N. . (2022). Efecto antidiabético de Atriplex halimus en tratamiento. corto. largo plazo contra la diabetes inducida por estreptozocina. Anales de Biología, (44), 21–30. https://doi.org/10.6018/analesbio.44.03
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