α-2 ADRENOCEPTOR AGONISTS FOR SEDATION AND VETERINARY ANAESTHESIA
Abstract
Sedative drugs are widely used in veterinary practice to chemically restrain patients undergoing minor and non invasive procedures. These drugs are also routinely administered for pre-anaesthesia due to its positive effects on the outcome of the general anaesthesia. The α-2 agonists are most important within these group of drugs due to its profound and reliable sedative properties as well as its good analgesic and muscle relaxant properties. Nevertheless, the α-2 agonist drugs also exhibit unwanted effects such as hyper/hypotension, second degree auriculo-ventricular blocks and bradychardia. Selective α-2 antagonist drugs are now marketed to reverse these adverse effects as well as to accelerate the recovery after using these drugs.Downloads
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