INTRAVENOUS PHARMACOKINETICS AND BINDING TO PLASMATIC PROTEINS OF OXYTETRACYCLINE IN PIGEONS (<i>COLUMBA LIVIA</i>)

Authors

  • J. M. Serrano
  • C. Ponferrada
  • M. A. Sanjuán
  • J. Hita
  • C. M. Cárceles
Keywords: oxitetraciclina, farmacocinética, unión a proteínas, paloma

Abstract

A kinetic survey of oxytetracycline has been carried out after intravenous administration in pigeons (Columba livia). After the corresponding pharmacokinetics studies results have shown a more correct adjustment to a monocompartimental pattern than a bicompartimental pattern, the numerical expression of this adjustement is as follows: Ct = 264.77 e-0.0189t mg/l In addition it has been found out the more important pharmacokinetics parameters for both compartimental patterns. Finally the binding of oxytetracycline to plasmatic proteins of pigeon has been studied resulting an average union percentage of 55.46% and an association constant of 13.21 mg/l (2.65 10-5 M/l.

Downloads

Download data is not yet available.

Author Biographies

J. M. Serrano

Departamento de Farmacología y Toxicología Universidad de Córdoba

C. Ponferrada

Departamento de Farmacología y Toxicología Universidad de Córdoba

M. A. Sanjuán

Departamento de Ciencias Socio-sanitarias Universidad de Murcia

J. Hita

Departamento de Ciencias Socio-sanitarias Universidad de Murcia

C. M. Cárceles

Departamento de Ciencias Socio-sanitarias Universidad de Murcia
How to Cite
Serrano, J. M., Ponferrada, C., Sanjuán, M. A., Hita, J., & Cárceles, C. M. (1988). INTRAVENOUS PHARMACOKINETICS AND BINDING TO PLASMATIC PROTEINS OF OXYTETRACYCLINE IN PIGEONS (<i>COLUMBA LIVIA</i>). Anales de Veterinaria de Murcia, 4, 77–82. Retrieved from https://revistas.um.es/analesvet/article/view/22381
Issue
Vol. 4 (1988)
Section
Trabajos Fin de Grado/Fin de Máster

 

Creative Commons Attribution 4.0

The works published in this journal are subject to the following terms:
1. The Publications Service of the University of Murcia (the publisher) retains the property rights (copyright) of published works, and encourages and enables the reuse of the same under the license specified in paragraph 2.

© Servicio de Publicaciones, Universidad de Murcia, 2019

2. The works are published in the online edition of the journal under a Creative Commons Attribution-NonCommercial 4.0 (legal text). You can copy, use, distribute, transmit and publicly display, provided that: i) you cite the author and the original source of publication (journal, editorial and URL of the work), ii) are not used for commercial purposes, iii ) mentions the existence and specifications of this license.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

3. Conditions of self-archiving. Is allowed and encouraged the authors to disseminate electronically pre-print versions (version before being evaluated and sent to the journal) and / or post-print (version reviewed and accepted for publication) of their works before publication, as it encourages its earliest circulation and diffusion and thus a possible increase in its citation and scope between the academic community. RoMEO Color: Green.