QUANTIFICATION AND EVOLUTION OF RABIES ANTIBODIES LEVEL BY ELISA IN DOG SERA WITH DIFFERENT NUMBER OF VACCINATIONS
Abstract
In the present study have been analyzed 253 sera samples from dogs with different number of anti-rabies vaccinations. The aim of this work has been to obtain dates that allow to detect and quantify the level of antibodies against rabies virus to know its evolution in refering to the numbers of vaccination. The method used has been ELISA, by considering that is rapid and safe and we can analize a great number of samples, therefore its sensitivity is comparable at seroneutralization methods. By simple correlation analysis (a = 0.05), the results obtained show no significant differences between vaccinated dogs in the first time and those vaccinated severa1 times, but a difference between the antibodies level (optical densities) in sera from vaccinated dogs and those non vaccinated animals, was found.Downloads
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