ACUTE PHASE PROTEINS: GENERAL CONCEPTS AND MAIN CLINICAL APPLICATIONS IN VETERINARY MEDICINE.
Abstract
The acute phase response is the reaction of the animal to disturbances in its homeostasis caused by infection, tissue injury, neoplastic growth or immunological disorders (KUSHNER et al. 1981). During this response there is a change in the concentration of some plasma proteins called Acute Phase protein. Proteins such as haptoglobin, C-reactive protein, serum amyloid A, ceruloplasmin, a1-acid glycoprotein and fibrinogen are included in this group. Investigations over the last years have shown that the cuantification of their concentration in plasma or serum provide valuable clinical information in the detection, prognosis and monitoring of disease (ECKERSALL 2000).Downloads
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