Simultaneos uterine leiomyoma and endomtiral hyperplasia in a white-nosed monkey (Cercopithecus Nictitans). First case report
Abstract
This paper describes histopathological and immunocytochemical features of a combined uterine leyomioma and a non atypical complex endometrial hyperplasia in a white-nosed monkey (Cercopithecus nictitans). Immunocytochemically, uterine leiomyoma was α-actin positive, and negative for desmin. By the other hand, endometrial hyperplasia showed strong immunoreaction against ciclin D1, cyclooxygenase-2 (COX-2), oestrogen receptor, isoform A of progesterone receptor and slight p53 immunoreaction. This is the first immunocytochemical description of an endometrial hyperplasia in a white-nosed monkey. This lesional spectrum, similar to those described in human pathology, suggests similar pathogenic mechanisms.Downloads
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