Brucellosis at the end of the XXth century. Is it necessary to develop a human vaccine?
Abstract
The aim of this work is to evaluate the results of offi cial eradication-campaigns of small-ruminants brucellosis infection (B. melitensis) carried out in Spain in recent years. Brucellosis offi cial eradicationcampaigns data were used the study the epidemiological situation of the small-ruminant brucellosis infection. Data of consecutive campaigns from offi cial information was contradictory and other data defi ciencies that might have been affected the campaign results that carried out an un-knowledge of the true epidemiological situation in some regions in Spain. An epidemiological statistical study between animal and human infection taxes showed that human brucellosis infection was not as a result of a direct animal contact. Despite of a decrease of the animal infection level, Spain presents the worst epidemiological situation of the European Union. A second objective has been to evaluate from the epidemiological situation in Europe and Spain the impact of brucellosis around Mediterranean area and in developed countries using Brucella sp. as a biological arm. A lack of human vaccine may be considered, despite low mortality as a candidate to be used as a bio-terrorism.Downloads
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