Investigation on mechanism of antifungal activity of citral against Cladosporium sphaerospermum Penz.
Abstract
El objetivo de este estudio fue investigar la actividad antifúngica del citral contra Cladosporium sphaerospermum, mediante la determinación de la concentración mínima inhibitoria (CMI) y la concentración mínima de fungicida (CMF), los efectos sobre el crecimiento micelial y la germinación de conidios, y también investigar la posible acción de citral en paredes celulares y membranas celulares. La CMI del citral varió de 128 a 256 µg/mL y la CMF varió de 256 a 1024 µg/mL. La CMI50 y CMF50 fueron, respectivamente, 128 µg/mL y 256 µg/mL. El citral inhibió el desarrollo micelial y la germinación de conidios y mostró interacción con ergosterol. Estos datos indican que el citral tiene una fuerte actividad antifúngica, que puede estar relacionada con su interacción con el ergosterol.
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