Study on impact of silver nanoparticles synthesized using aqueous extract of Ganoderma applanatum on thyroid and lipid parameters of albino rat

Impact of silver nanoparticles on thyroid and lipid profile

Authors

  • Sukumar Dandapat Ranchi University
  • Rohit Srivastava Department of Zoology, Ranchi University, Ranchi-834008, Jharkhand, India
  • Manoranjan Prasad Sinha Department of Zoology, Ranchi University, Ranchi-834008, Jharkhand, India
DOI: https://doi.org/10.6018/analesbio.43.14
Keywords: Nanoparticles, Hormone, Lipid, Thyroid, Cholesterol

Abstract

Impact of silver nanoparticles loaded with Ganoderma applanatum extract on thyroid and lipid profile of rat were studied. Synthesized SNPs (Average diameter 58.77 nm; -13.8 mV zeta potential) were analysed by dynamic light scattering analysis. Fourier transform infrared spectroscopy provided broad and high transmission peak at 3248.12 cm-1 which indicates the loaded biochemical of the G. applanatum extract on the surface of SNPs. No mortality and behavioural changes were observed in the Acute toxicity test. Group-1 received 1 mL distilled water, group-2 and group-3 received 200 mg kg-1 and 400 mg kg-1 nanoparticles respectively. A 400 mg kg-1 dose of SNPs showed increased hyper thyroid and hypolipidimic activity as compared to control and 200 mg kg-1 dose.

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Published
09-11-2021
How to Cite
Dandapat, S., Srivastava, R., & Sinha, M. P. (2021). Study on impact of silver nanoparticles synthesized using aqueous extract of Ganoderma applanatum on thyroid and lipid parameters of albino rat: Impact of silver nanoparticles on thyroid and lipid profile. Anales de Biología, (43), 139–152. https://doi.org/10.6018/analesbio.43.14
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