Effects of particulate matter under behavioral, hematological and biochemical parameters in Wistar rats
Abstract
Particulate matter (PM) can alter the cognitive processes, the depressive behavior, and the hematological profile in animals. This study aimed to evaluate the effects on behavioral, hematological, and biochemical parameters caused by PM in an animal model. A significant decrease in the locomotion activity of Group 3 (PM10) in relation to Group 1 (Control) and Group 2 (PM2.5) was observed. Regarding the anxiety behavior, Group 3 remained significantly the most part of the time in the open arms when compared to the control and PM2.5 groups. No hematological or biochemical alterations were observed among groups. In this study, we concluded that the exposure to particulate matter can cause neurological damages, and consequently, affect other systems.
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