INTERFERON: BIOCHEMICAL MECHANISMS OF FORMATION AND ACTION

Authors

  • Jesús D. Galindo
  • Francisco Solano
  • José L. Iborra

Abstract

The group of proteins known as interferons is now one of the most important fields of research in Biology. This review summarizes our present knowledge about the biochemical mechanisms of synthesis and action of interferons. Discovered by Isaacs and Lindenmann as agents of vira1 interference, today it is known that they are produced by most of vertebrates in response to a lot of appropiate stimuli. Here we discuss the classification of interferons, the human genes in which the information for their production and for the protein machinery involved in their response is contained, the biochemical mechanisms of the interferon production in cues treated by an inductor, and those developed in the surrounding cells when interferon is secreted. We conclude with the expression of therapeutic use of interferon and the existence of similar proteins in vegetal species.

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Author Biographies

Jesús D. Galindo

Departamento lnterfacultativo de Bioquímica Universidad de Murcia Murcia

Francisco Solano

Departamento lnterfacultativo de Bioquímica Universidad de Murcia Murcia

José L. Iborra

Departamento lnterfacultativo de Bioquímica Universidad de Murcia Murcia
How to Cite
Galindo, J. D., Solano, F., & Iborra, J. L. (1985). INTERFERON: BIOCHEMICAL MECHANISMS OF FORMATION AND ACTION. Anales de Biología, (5), 3–15. Retrieved from https://revistas.um.es/analesbio/article/view/35182
Issue
Section
Biología general