Collagen-platelet interaction: platelet non-integrin receptors

Authors

  • Thomas M. Chiang

Keywords:

receptor, platelet, collagen, signal transduction, protein phosphorylation

Abstract

Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These nonintegrin receptors also serve as signal transducers both from the outside of platelets to the inside and possibly vice versa. The present review covers basic aspects of non-integrin receptor function and various signal transduction pathways.

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Invited Reviews