Genomic imprinting and Beckwith-Wiedemann syndrome

Authors

  • lzuho Hatada
  • T. Mukai

Keywords:

genomic imprinting, imprinted, Beckwith-Wiedemann syndrome, p57K1P2, IGF2, llp15

Abstract

Genomic imprinting is the parental-allelespecific expression of genes. Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth syndrome with increased risk of childhood tumors, is one of the well-known diseases caused by imprinted genes. The imprinted genes causing BWS are discussed in this review.

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Invited Reviews